The epidemic rates of increase in the prevalence of obesity have spawned an entire industry of fad diets. Typically these diets restrict one specific food group and/or severely restrict caloric intake. Although consumers do lose weight they quickly get tired of having their food choices limited, consequently they go off of their diet, usually within 2 months, and gain back everything and usually more just as quickly as they lost it. The next fad diet comes along and the consumer starts over again and the cycle repeats itself. Over a decade or two there may be a series of these diet cycles that at some point begin to look like the ups and downs of a yo-yo. Unfortunately, when weight is lost, both fat and muscle mass are lost. When the weight comes back, it is predominantly fat. Consequently, with each cycle more fat is stored and more muscle is lost which is not good for the dieter's health. This yo-yo effect also makes future weight loss more difficult as it is more difficult for the dieter to burn the stored fat because of their reduced muscle mass. It also needs to be appreciated that, individuals with a history of weight yo-yoing are at an increased risk of developing type 2 diabetes. Consequently, maintaining the weight loss is more important than the weight loss itself, in the long run.
Dietary fibers have been purported to assist in weight loss. However, the real effects have been negligible until alpha-cyclodextrin was proposed for use in weight loss and management. Alpha-cyclodextrin is a naturally occurring, soluble fiber derived from corn. When ingested with fat-containing meals, it forms a very stable complex with dietary fat in the stomach. As this fiber is not absorbed into the blood stream it has no effect on brain chemistry or metabolic functions. Fat that is bound into a complex with alpha-cyclodextrin is not available for absorption into the blood stream. As the fat remains bound while passing through the large bowel there are no unwanted intestinal side effects. Published clinical trial and animal studies have demonstrated that this particular fiber is not only effective in assisting weight loss, but also is effective in reducing both total and LDL (bad) cholesterol as well as increasing insulin sensitivity, thus reducing the risk of developing cardiovascular disease and type 2 diabetes.
Alpha-cyclodextrin is not only effective for weight loss, but also effective for weight maintenance. Once a person has reached their desired weight, with or without alpha-cyclodextrin, the fiber can be used to maintain that weight thus preventing the next upward swing of the yo-yo. For the first time, dieters have a safe, effective and simple way to maintain their desired body weight.
Taken as directed, six grams per day will reduce caloric absorption by about 500 calories/day. This is equivalent to approximately 50-60 percent of the fat or 25-30 percent of calories from the typical Western diet. As a result, even though the consumer has physically stopped dieting they are able to maintain their desired weight by regulating the absorption of the fat that they consume.
How It Works
When taken with a fat-containing meal, the alpha-cyclodextrin fiber mixes with and complexes to, 9 times its own weight of the consumed fat. The bound fat passes through the small bowel without being absorbed and through the large bowel without being fermented by the normal bacteria of the bowel. The fat-fiber complex is eliminated, unnoticed, with the next movement. Since the fiber is not absorbed into the blood stream, it will never alter brain function or affect the metabolism of drugs, hormones or metabolites.
Study Results
Clinical studies conducted with either obese type 2 diabetics or overweight, but not obese non-diabetic volunteers have produced very promising results. These investigations confirm the beneficial effects of alpha-cyclodextrin on weight loss/management as well as the elevated blood lipid levels that have been implicated in the development of numerous chronic disease states, including type 2 diabetes, hypertension and cardiovascular disease. The data also shows that, in the absence of any changes to diet or exercise regimes, significantly more weight was lost by the volunteers during the active phase as compared to the control phase of the study. Blood total and LDL (bad) cholesterol, as well as the proatherogenic Apolipoprotein B levels were significantly reduced in the active phase of the study while HDL (good) cholesterol levels remained unchanged. Blood insulin levels were reduced in the active phase, which may indicate a reduced risk of developing type 2 diabetes. Unlike any other studied weight loss product, the study participants were not put on a low calorie diet.
To view all of the studies, or to learn more visit mirafit.com mirafit.com.
Joseph D. Artiss, Ph.D., FACB
Is Vice President of ArtJen Complexus Holdings Corp.
Windsor, ON N9A 6V2, Canada,
Co-Inventor of Mirafit fbcx
And
Associate Professor of Pathology
Wayne State University
Detroit, MI 48201 USA
and
K-L Catherine Jen, Ph.D.
Is President of ArtJen Complexus Holdings Corp.
Windsor, ON N9A 6V2, Canada,
Co-Inventor of Mirafit fbcx
And
Professor and Chair of Department of Nutrition and Food Science
Wayne State University
Detroit, MI 48202 USA
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